Scientific supervisor: PhD in Biological Sciences, Assoc. Hovhannisyan A.A.
Directions of the laboratory's research activities:
-
Analysis of phytocomponents of various extracts of ethnic plants of the Armenian flora;
-
Research of cytotoxic, cytostatic, antioxidant, anti-infective and anti-tumor antidotes, etc. properties of medicinal plants identification of their active components and biochemical mechanisms of action;
-
Chemical synthesis and design of nanoparticles with broad therapeutic activities;
-
Biogenic synthesis of non-toxic core-shell nanoparticles and their application;
-
Study and identification of parameters and type of interactions of biologically active low molecular weight compounds of secondary metabolism of plants and their semi-synthetic derivatives with canonical and non-canonical forms of DNA by methods of molecular dynamics; with transcription regulators, nuclear trans factors;
-
The use of in silico methods for the construction of new pharmacophores with low genotoxicity, cytotoxicity and side effects, compared with clinical analogues;
-
Obtaining callus cultures of endemic plants of the Armenian flora, in order to study and increase the efficiency of the synthesis of secondary bioactive metabolites;
-
Microclonal reproduction of plants.
Educational activities: on the basis of the laboratory, special courses, laboratory, practical, as well as pre-graduate practical classes are held for teaching students of the departments of "Medical Biochemistry and Biotechnology", "Bioengineering and Bioinformatics", "Pharmacy" in specialized disciplines.
Modern material and technical equipment of the laboratory allows students and postgraduates to carry out scientific work for the preparation of term papers, final qualifying, master's and dissertation works.
Partner universities and research centers (collaboration): St. Petersburg Polytechnic University named after Peter the Great, Stavropol State Medical University, Laboratory of Protein Engineering of SIC "Kurchatov Institute".