team

Назарян Карен Бабкенович

д.б.н., профессор

Описание

Доктор биологических наук, и.о. профессора кафедры биоинженерии, биоинформатики и молекулярной биологии Института Биомедицины и Фармации Российско-Армянского Университета
Зав. лабораторией капютерного моделированиея Института молекулярной биологии НАН РА

Образование:
1973-1977 Научный центр психического здоровья АМН СССР, аспирант, Москва
1966-1971  Отд.биофизики биол.ф-та ЕГУ , студент  Ереван

Работа :
1977-н/в  Институт молекулярной биологии НАН РА, Лаборант, м.н.с.,с.т.с, зав.лаб, Ереван
1992-1996  Институт биохимии Ун-та Женевы, Швейцария, Асс. профессор, Женева
2007-н/в   Российско-Армянский Университе, и.о. профессора, Ереван



 

Список основных публикаций

  • 1. Muradyan N, Arakelov V, Sargsyan A, Paronyan A, Arakelov G, Nazaryan K. Impact of mutations on the stability of SARS-CoV-2 nucleocapsid protein structure. Sci Rep. 2024 Mar 11;14(1):5870. doi: 10.1038/s41598-024-55157-8
  • 2. Sargsyan A, Sahakyan H, Nazaryan K. Effect of Colchicine Binding Site Inhibitors on the Tubulin Intersubunit Interaction. ACS Omega. 2023 Aug 3;8(32):29448-29454. doi: 10.1021/acsomega.3c02979.
  • 3. Sahakyan H, Nazaryan K, Mushegian A, Sorokina I. A Study of a Protein-Folding Machine: Transient Rotation of the Polypeptide Backbone Facilitates Rapid Folding of Protein Domains in All-Atom Molecular Dynamics Simulations. Int J Mol Sci. 2023 Jun 13;24(12):10049. doi: 10.3390/ijms241210049.
  • 4. Abrahamyan A, Eldstrom J, Sahakyan H, Karagulyan N, Mkrtchyan L, Karapetyan T, Sargsyan E, Kneussel M, Nazaryan K, Schwarz JR, Fedida D, Vardanyan V. Mechanism of external K+ sensitivity of KCNQ1 channels. J Gen Physiol. 2023 May 1;155(5):e202213205. doi: 10.1085/jgp.202213205
  • 5. Forouharmajd F, Nazaryan K, Fuente A, Pourabdian S, Asady H.The Efficiency of Hearing Protective Devices against Occupational Low Frequency Noise in Comparison to the New Subjective Suggested Method. Int J Prev Med. 2022 Nov 23;13:143. doi: 10.4103/ijpvm.IJPVM_700_20
  • 6. Al-Sanea MM, Chilingaryan G, Abelyan N, Arakelov G, Sahakyan H, Arakelov VG, Nazaryan K, Hussein S, Alazmi GM, Alsharari HE, Al-Faraj WM, Alruwaili FS, Albilasi NQ, Alsharari TS, Alsaleh AAS, Alazmi TM, Almalki AH, Alotaibi NH, Abdelgawad MA. Identification of non-classical hCA XII inhibitors using combination of computational approaches for drug design and discovery. Sci Rep. 2021 Jul 30;11(1):15516. doi: 10.1038/s41598-021-94809-x.
  • 7. Chilingaryan G, Abelyan N, Sargsyan A, Nazaryan K, Serobian A, Zakaryan H. Combination of consensus and ensemble docking strategies for the discovery of human dihydroorotate dehydrogenase inhibitors. Sci Rep. 2021 Jun 1;11(1):11417. doi: 10.1038/s41598-021-91069-7
  • 8. Sirakanyan S, Arabyan E, Hakobyan A, Hakobyan T, Chilingaryan G, Sahakyan H, Sargsyan A, Arakelov G, Nazaryan K, Izmailyan R, Abroyan L, Karalyan Z, Arakelova E, Hakobyan E, Hovakimyan A, Serobian A, Neves M, Ferreira J, Ferreira F, Zakaryan H. A new microtubule-stabilizing agent shows potent antiviral effects against African swine fever virus with no cytotoxicity. Emerg Microbes Infect. 2021 Dec;10(1):783-796. doi: 10.1080/22221751.2021.1902751.
  • 9. Sahakyan H, Nazaryan K, Mushegian A, Sorokina I. Energy-dependent protein folding: modeling how a protein folding machine may work. F1000Res. 2021 Jan 5;10:3. doi: 10.12688/f1000research.28175.1. eCollection 2021.
  • 10. Sahakyan H, Abelyan N, Arakelov V, Arakelov G, Nazaryan K. In silico study of colchicine resistance molecular mechanisms caused by tubulin structural polymorphism. PLoS One. 2019 Aug 23;14(8):e0221532. doi: 10.1371/journal.pone.0221532.

Дисциплины